RNA Details
Disease Name
pulmonary fibrosis
Tissue
lung
RNA Symbol
Il6
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
qRT-PCR; Microarray Analysis etc.
Target
NA
Pathway
NA
PubMed ID
Title
Inhibition of nuclear factor kappaB in the lungs protect bleomycin-induced lung fibrosis in mice
Year
2022
Function
"The mRNA expression of proinflammatory cytokine genes; IL6, IL1beta and RelA were increased by 2.52 +- 0.31-, 2.32 +- 0.06 and 3.01 +- 0.5 (P < 0.05)-fold, respectively, in the lungs of BLM-treated WT mice, compared with the untreated WT mice."